The year is 1851 and assassin brothers Charlie and Eli Sisters find themselves journeying through the Northwest with the blood of both criminals and innocent folks on their hands. While the determined and ruthless Charlie assumes the position of leader in their assignments, reflective Eli still dreams of a normal life, causing the pair to squabble often. As the brothers make their way through Oregon's mountains and California Gold Rush territory, their remaining humanity and the familial ties that bond them will be tested. "The Sisters Brothers," in theaters Sept. 21, 2018, is rated R.

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Jake Gyllenhaal ... John Morris, Joaquin Phoenix ... Charlie Sisters, John C. Reilly ... Eli Sisters, Riz Ahmed ... Hermann Kermit Warm, Carol Kane ... Mrs. Sisters, Rebecca Root ... Mayfield, Rutger Hauer ... The Commodore
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Jacques Audiard ... Director
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